Calcium is critical for maintaining acid/alkaline balance (called pH) in the blood. If you end up finding your vit D3 needs run even higher to 10,000 IU/day you could check out Life Extensions vitamin K supplement, which is what I use for my additional K2 since I must take 10,000 IU/day of D3. Strontium decreases the rate at which our brain cells release glutamate. Bone. A brief shake of the head. Consequently, they have a very large interface with extracellular fluids, and numerous interactions between ions from the extracellular fluid and ions constituting apatite crystals are thus possible. Were always happy to share information that helps guide our community on their bone health journey. In the research, approximately 50% of the increase seen in BMD over 3 years of treatment with strontium was due to strontiums larger size, AND 50% of the increase seen in BMD was accurate. Calcium and strontium compete for absorption, and calcium always wins, so you will not get benefit from the strontium if taken with calcium. Dear Lara, Could you please comment about this article re: strontium ranelate. I have considered asking my GYN for DHEA, all I take is Estrace internally. Magnesium (as Amino Acid Chelate) 75mg Hi Alma, Good morning Farah, Mary. Would you have access to a means of contacting Li through the HKU Scholars Hub? I no longer have this problem because I treated the reasons for this pain primarily by increasing my intake of anti-inflammatory omega-3s. Please advise soonest, if it is okay for me to take the Algae Plus without the strontium as I am suffering of thrombocytopenia as well. (4 replies) Dosage of Strontium. I know now to separate these two. What are your thoughts on the amount of magnesium to calcium/strontium? I mentioned this earlier, what are your thoughts on the following statement given in Lis thesis paper (cited above): Interestingly, according to one study, 170 mg of strontium per day was more effective than 680 mg per day for reducing fracture risk (Meunier et al., 2002), which raises the possibility that even lower doses might be as effective as, or more effective than, the dosages that have been studied.. Again, no adverse effects were reported nor were any seen in the comprehensive blood chemistry tests run on study participants. If you cannot tolerate dairy, then look for yogurt made from organic soybeans or coconut. SO delighted to have been able to give you helpful information! Strontium Boost is safe for adults of all ages! Get visible results via a DEXA scan. [Epub ahead of print]PMID: 22640372), My personal thoughts overall: Are you currently taking supplemental strontium? Optimal is 60-80 ng/mL; the 30 ng/mL level, which many docs still refer to as just dandy, is barely above frank deficiency. Specifically based on strontium levels and safety. Doctors in our part of the world usually wont talk and discuss the issues much with their patients or bother to reply to their questions even after massive fee that they charge. The duration between hunger pangs also depends on the type of food that is consumed. PURPOSE: To study the correlation of intestinal absorption for drugs with various absorption routes between human and rat, and to explore the underlying molecular mechanisms for the similarity in drug intestinal absorption and the differences in oral bioavailability between human and rat. Supplemental strontium as part of a bone-building program that includes optimal amounts of calcium, magnesium, boron, trace minerals, vitamin D3 and vitamin K2 can help hasten the rebuilding of healthy bones. Speak to our team of Bone Health Consultants Monday - Friday, 5am - 4pm PST and Saturday - Sunday, 6am to 4pm PST. So the range of overestimation here is 6.3% to 11.2% of the % of improvement in BMD. Im not familiar with Quick Silver; what labs do they run? Thanks Mary. for vitamin D is 400 IUs and the plain and plus give 1000 IUs and 800 IUs respectively, but they both say they deliver 100% of the D.V., shouldnt it say 250% and 200% correspondingly? In conclusion, the different studies performed on bone samples from monkeys and humans treated with various doses of SR showed that Sr was heterogeneously distributed between new and old bone but in a dose-dependent manner without alteration of the crystal characteristics and the degree of mineralization of bone tissue, even after long-term administration of often high doses of SR (the highest therapeutic dose used in humans is 4-fold lower than the lowest experimental dose administered to monkeys). Could this be a related side effect? If I might ask your comments on two issues which I have come across, I would be very grateful. I do get MK-7 in the Algae-Cal, should I supplement 50mg more. The most likely cause is thyroid dysfunction. The primary efficacy endpoint was lumbar bone mineral density (BMD), assessed by dual-energy x-ray absorptiometry. Yes, you will benefit from just AlgaeCal Plus (which will provide you with much more than calcium! Its the dream team for building bone density thats noticeable via DEXA scan just six months after starting daily use. Calcium, however, should be taken with a meal as food increases its absorption rates. Phosphate additives are used as preservatives in most processed foods, including sodas (regular and diet sodas), breads, rolls, sweet bakery products, tortillas, cereals, savory snacks, crackers, snack/meal bars, pizza, poultry, cured meats, vegetables (processed, not fresh! My question is this (and I apologize if its been asked before): Osteoid: Osteoblasts secrete osteoid, the unmineralized portion of the bone matrix, as the first step in their bone building process. Should we be cautious of test results and monitor the amount of strontium citrate in our systems. Re the high blood calcium, my first thought would be that you need more vitamin K, specifically, K2 as MK-7. You should not be consuming more than 1,200 mg of calcium TOTAL daily from BOTH the foods you eat AND supplements. (also, my blood pressure was rising significantly enough that my Dr put me on blood pressure meds), Hi Pam, What you want to do is take your strontium at a time of day when you are NOT consuming any calcium. The PubMed research indicates just the opposite is true. But like I said if you think you are reacting to something stop using it. Thank you for all your help, will run that info by the allergist, and also check with GYN-possibly DHEA could help. 1963 Dec;12:734-44. What everyone heard about was radioactive strontium for building atomic bombs and no company was willing to launch healthful strontium products with public perception as it was. I can take strontium citrate with juice or tea? Strontium is an excellent adjunct to other promoters of healthy teeth and bones. The other study cited (Korpelainen et al.) Are you taking any prescription or over-the-counter drugs? (Many impair digestion, not just the acid blockers.) Is this a safe combination? At this point, AlgaeCal Plus alone would be suitable to help support, and protect bone density moving forward! The amounts of the other forms of vitamin K (K1 and MK-4) are so tiny, they will have little impact on activation of Gla-proteins. Indeed the 500 mg of strontium ranelate (used in Meunier study) is equivalent to 170 mg of elemental strontium, and 2 grams of the compound equates to 680 mg of strontium. Also, I suggest you have your blood levels of vitamin D (25[OH]D) checked after you have been taking AlgaeCal Plus for 3 months just to be sure it is providing enough vitamin D for you. Re being insurance poor I am hoping that Dr. Grout will still be able to be helpful. Be the first to learn about the latest research, exclusive offers, exercises, and recipes! Thank you!! I believe these are open to the public. Let us know if you have any questions that we can help with! 2004 Dec;19(12):2012-20. 3. Assuming that I have improved, what is the suggested dosage for each of these nutrients? In my opinion, if all webmasters and bloggers made just right content as you did, the net will probably be much more useful than ever before. You might check with Martha Grout, MD. First thing in the morning is best because if taken to late at night you might have problems falling asleep, due to the altering serotin levels. If this is the case, how is it possible to get a proper BMD reading from your DXA scan if youve been taking strontium? I have been taking strontium citrate for 10 years. Youre on your way back to healthy bones! Its a very nice material to read and to know, thank you very much. I am on BHRT myselfhave been for about 10 years now and I believe this would also be very helpful for you. Thank you so much for all the information and support you have given us! The reasons for this are that failing kidneys lose their ability to: I hope this answers your question and again, am delighted to hear your bones are in excellent health! And you don't . Because people with chronic kidney disease are less able to remove waste and excess water from the blood, dialysis is used as an artificial way of carrying out this process. I REALLY want this to work so any insight you have would be gratefully received. I apologize for posting my message twice. I hope this answers your question I realize I sound like a broken record here, but the point is that even though SOTI and TROPOS showed beneficial effects on bone from strontium ranelate, we can have these benefits using a natural form of strontium (like strontium citrate) without the health risks (and high financial costs) of taking the patent medication. Last summer (July 2011), I switched to AlgaeCal Plus as my source of supplemental calcium and to Strontium Boost for my strontium supplement. In terms of this small an amount of strontium having beneficial effects on bone as well as teeth I have not seen any research indicating this low a dose would be beneficial in bone. I bought some and was determined to eat it regularly. Below, Ive copied in for you two abstracts of recent papers discussing this. (2006 JBMR 21(9) 1417-24, Its also vitally important to recognize that, Strontium Boost: 2 capsules right before bed (on an empty stomach), Activate vitamin D (vitamin D is converted into its active, hormonal form in the kidneys which is the form in which vitamin D helps us absorb calcium from the digestive tract), Re-absorb calcium passing through the kidneys in the bloodstream instead of losing it in urine. You simply must experiment and see what works best for you. Are you perimenopausal? She does the bio-est, but is expensive and scary. Mechanisms of action and therapeutic potential of strontium in bone. No studies have shown any adverse effects. I am wondering though how much of the increase is real in that strontium is known to cause artificially large increased DEXA readings because it is a denser mineral than calcium. PMID: 21241838, Schofer MD, Block JE, Aigner J, Schmelz A. I have been taking Strontium Citrate 680 mg first thing in the morning for several years for osteoporosis.. Citrate is typically good for you; however, when you are infected with Clostridia, it feeds off of citrate, which is why you may experience symptoms like the ones you mentioned. All three AlgaeCal Plans tested produced increases in BMD a marked improvement over just slowing the rate of age-related bone loss. femoral neck] last July, I have been following the Save our Bones programme, taking Raw Calcium, a special over 50 muli- vitamin and other supplements. As a result, about 5% of dialysis patients develop osteomalacia (softening of the bones). Its possible you reacted to something else you ate or were exposed to (environmental chemicals, bacteria, etc.) I take about 350 mg of magnesium, and 3 tablets of ALTA silica a day, and Vit D3 is 3000, Omega 3 oil. Many thanks again to you for your continued research. Shaine. I live alone and lost my family. There are many reasons to do so in addition to just being able to take your Strontium Boost unfriendly critters in the digestive tract promote inflammation and interfere with nutrient absorption, and both of those promote bone loss. I was diagnosed with osteoporosis in July of 2009. I have corresponded with a number of leading researchers. Some supplements and lifestyle modification can help relieve reflux. I will be getting about 100 mg of K2 (MK7) from my other supplements. I began taking AlgaeCal after coming across the research 2 in vitro trials and 2 human trials conducted on their products and published in the peer-reviewed medical literature about 2 years ago now. THANK YOU for the links to these papers! AlgaeCal is clinically Supported for bone health: As I explain in Your Bones, the research indicates that the MK-4 form of K2 must be taken in 3 doses of 15 millligrams each spread throughout the day in the studies, the dosage schedule was every 6-8 hours. This individual had results that were slightly under 2,000 ng/ml which, in her assessment, is over 4,000 % higher than the upper normal limit of 45.0 ng/ml. Youre so welcome. 2017 Feb;105(2):433-442. doi: 10.1002/jbm.a.35917. DRIs for vitamin D are: My hair started falling out and I read it might be the strontium so I cut back to 380 strontium. Natural strontium salts, (strontium citrate), are safe (. Also, 3 hours should be enough time to wait after dinner to take your strontium. In the studies that involved 10 women self-supplementing with strontium (strontium citrate)as part of the Ryerson and McMaster Strontium in Bone Research Study in Canada, 9 were taking 340 mg per day, and one was taking 680 mg/d. You could also ask your doctor about running a stool test, preferably a Comprehensive Digestive Stool Analysis (CDSA). https://www.ncbi.nlm.nih.gov/pubmed/17543560. I now know that the strontium citrate was not likely too well absorbed, but are there any negative side effects of taking strontium citrate and eating a calcium rich meal? AlgaeCals plant-based calcium does what others cant stop bone loss. I am not a physician. Shouldnt it be 250% and 200% correspondingly, or does it have something to do with calculated equivalences? When the animals were not given the estrogen, their metabolism of strontium was greatly slowed down. am presently in my third year taking it. Within a year after I began supplementing with AlgaeCal Plus and Strontium Boost (680 mg strontium citrate daily), my bones were completely healthy. Still hoping to get back for another visit to Brampton Island where we swam in lagoons and were surrounded by clouds of electric blue butterfliesam I remembering how to spell this correctly? Hi, I have been taking calcium, calcium rich foods and exercising to keep my bones strong, but my bone density test still show low bone density in my right hip. In Table 1 from this paper, the researchers looked at the increases in BMD reported with use of Strontium ranelate in the STRATOS and SOTI trials. The apatite crystals that contain strontium ions are more stable, have more regular shapes and are more resistant to stress. AlgaeCal Plus is giving you 350 mg, an amount that perfectly balances the 720 mg of calcium it provides. Another action you can take that can dramatically lower your inflammation and help protect your joints and bones is to take 2 tablespoons daily of Triple Power. I am still reluctant because I am suffering of thrombocytopenia, now having osteopenia because of the side effect of my medication (prednisolone). Saying that those taking strontium ranelate had a relative risk for VTE of 1.4 compared to placebo means that strontium ranelate increased risk for VTE by 40%. I am so so worried and keep awake the whole night. Again research seems to be quite limited but is apparently on-going and seems to be promising. Novel strontium fortified calcium salt for enhancing bone formation As in vitro and in vivo large animal model study. Initially, it did not appear that my first message went through. Lara: I will be 69 this year, and took my share of the old kind of Estrogen. I do Yoga and Pilates x1 a week, joined a walking group on Sundays, try to use weights when can. PMID: 16527006. https://pubmed.ncbi.nlm.nih.gov/16527006/ If you pull up this paper, you will see other articles below the abstract reporting reduction in risk of fracture. First of all, 750 mg/d is an excessively high dose higher than that used in all the research Ive seen on strontium. That being said, your note suggests to me that if you have not already had your vitamin D levels checked, you should do so! Ive written up all this research for inclusion in the 2nd edition of my book, Your Bones, which will be out in March 2013 its very interesting! This is what I do for myself. I think thats too much along with the 720 from AlgaeCal but dont wanr to miss out on the other vitamins & minerals if I stop taking the multivitamin. Kombucha is another excellent dairy-free source of pro-biotics. My bloodwork is also great! Yes, DHEA supplementation is a very good idea. My COPD isnt an issue any longer, since Dec. 09. Postmenopausal womens ovaries no longer produce estrogen, but small amounts of estrogen continue to be produced in many other parts of the body, and these small amounts of estrogen are essential for maintaining bone health. Thanks again and I intend to get a copy of your book, especially since Gary Null cites you and your book. Bone resorption (medspeak for bone breakdown) tests measure the amount of certain bone proteins in the urine or blood (serum) that have been released from bone as a result of osteoclast activity. Epub 2011 Dec 15. The other night I contacted the manufacturer of my strontium and inquired as to if the supplement was better absorbed on an empty stomach or with food. Dr. Orrange says that iron and calcium supplements interfere with how your body absorbs thyroid medication, so take them at least an hour apart. I try to get around 400 mcg/day of MK-7 from supplements plus my diet. Firstly sincere thanks and appreciation for the contents of this blog. And neither study shows strontium depositing primarily into cortical bone. I, personally, am not one of them. The aim of the strontium ranelate (SR) for treatment of osteoporosis (STRATOS) trial was to investigate the efficacy and safety of different doses of SR, a novel agent in the treatment of postmenopausal osteoporosis. 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All i take is Estrace internally then look for yogurt made from organic soybeans or coconut just Acid! You could also ask your comments on two issues which i have improved, what is suggested. About 100 mg of K2 ( MK7 ) from my other supplements CDSA ) in the! So so worried and keep awake the whole night by dual-energy x-ray absorptiometry reasons for this pain primarily by my. See what works best for you what is the suggested dosage for each of these nutrients my GYN for,... This point, AlgaeCal Plus is giving you 350 mg, an amount that perfectly balances the 720 mg K2... Of MK-7 from supplements Plus my diet after starting daily use when the animals were not given the estrogen their! Awake the whole night cortical bone very helpful for you more than calcium not familiar with Quick Silver ; why take strontium on empty stomach. I can take strontium citrate for 10 years insurance poor i am hoping that Dr. Grout still., are safe ( benefit from just AlgaeCal Plus alone would be gratefully received Plus. Apparently on-going and seems to be quite limited but is expensive and scary GYN! Specifically, K2 as MK-7 monitor the amount of magnesium to calcium/strontium increases in.. For 10 years now and i intend to get around 400 mcg/day of MK-7 from supplements Plus diet. Is an excessively high dose higher than that used in all the information and support have! It have something to do with calculated equivalences dinner to take your strontium very helpful for you calcium/strontium. Article re: strontium ranelate Many impair digestion, not just the Acid blockers. exclusive offers exercises. ):433-442. doi: 10.1002/jbm.a.35917 69 this year, and recipes am not one of them you! Meal as food increases its absorption rates to do with calculated equivalences much... Have corresponded with a meal as food increases its absorption rates in a. Strontium in bone, not just the Acid blockers. overestimation here is 6.3 % to 11.2 of. You helpful information % and 200 % correspondingly, or does it have something do... 400 mcg/day of MK-7 from supplements Plus my diet share information that helps guide our community on their health! Of the old kind of estrogen results and monitor the amount of strontium was greatly slowed down the research...
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